Here, we investigated the effect of Tamarindus indica pulp aqueous extract (TIE) in diet-induced obese selleck kinase inhibitor Sprague-Dawley rats. The animals were divided into five groups and labeled as follows: the normal control (NC)
group received normal diet; the positive control (PC) group received high-fat diet; and the TIE 5, 25, and 50 groups, after the induction of obesity via a high-fat diet, received TIE at 5, 25, or 50 mg/kg orally for 10 weeks. It was observed that TIE decreased the levels of plasma total cholesterol, low-density lipoprotein (LDL), and triglyceride, and increased high-density lipoprotein (HDL), with the concomitant reduction of body weight. Moreover, TIE decreased plasma leptin and reduced fatty acid synthase (FAS) activity and enhanced the efficiency of the antioxidant defense system. TIE exhibits antiobesity effects, as indicated by a significant reduction in adipose tissue weights, as well as lowering the degree of hepatic steatosis in the obesity-induced rats. The extract possesses hepatoprotective activity, as it reversed the plasma liver enzymes level elevation prior to the high-fat diet. In conclusion, TIE improved obesity-related
parameters in blood, liver, and adipose tissue in a rat model and suppressed obesity induced by a high-fat diet, possibly by regulating lipid metabolism and lowering plasma leptin and FAS levels. A dose-dependant effect of TIE is detected, where TIE at 50 mg/kg showed the most prominent effect, followed by TIE at 25 mg/kg and, subsequently, MK-4827 mw 5 mg/kg.”
“The mechanism to realize high luminous efficacy in a plasma display panel fabricated with a cathode see more material possessing a high secondary electron emission coefficient (gamma) for Ne and Xe ions was studied via three-dimensional numerical simulation. When a high gamma cathode material is used, the increased electron heating efficacy is responsible for increasing vacuum ultraviolet (VUV)
efficacy with 10% Xe content gas. However, the continued availability of sufficient secondary electrons during the dynamic moving phase of the cathode sheath in which the electric field remains weakened causes increasing VUV efficacy with 30% Xe content gas. It was found that the improvement of the luminous efficacy of the plasma display panel with a high gamma cathode material is maximized under the condition of high Xe content gas because of the simultaneous increase of the electron heating efficacy and Xe excitation efficacy. (C) 2011 American Institute of Physics. [doi:10.1063/1.3626455]“
“Purpose: This study aimed to verify the low complication rates (0% to 11%) previously reported in cranial reconstruction using hard-tissue replacement patient-matched implant (HTR-PMI).
Patients and Methods: A 3-year multidisciplinary experience involving 21 patients undergoing HTR-PMI reconstruction of large cranial defects was reviewed. Complications were defined as implant exposure, implant infection, or soft-tissue infection.